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Sheftell, Fred D.; Bigal, Marcelo E.

CONTINUUM: Lifelong Learning in Neurology: December 2006 - Volume 12 - Issue 6, Headache - p 153-169
doi: 10.1212/01.CON.0000290528.77697.52

Medication overuse headache is considered to be the result of an interaction between an exposure (overuse of analgesics) and a biologically vulnerable individual (migraineur). Several lines of evidence suggest that in migraineurs, but not individuals without migraine, medication overuse is a risk factor for chronic daily headaches. Therefore, medication overuse headache should be prevented. In individuals with already established daily headaches and medication overuse, treatment requires a comprehensive plan that includes education, establishment of realistic goal, detoxification, and aggressive nonpharmacological and pharmacological preventive strategies.

© 2006 American Academy of Neurology
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