Category: TumorMicrosurgery of Insular Gliomas: Part III: Pathophysiology and Clinical PresentationYaşargil, Gazi M. M.D.; Krisht, Ali F. M.D.; Türe, Ugur M.D.; Al-Mefty, Ossama M.D.; Yaşargil, Dianne C.H. R.N.Author Information Dr. Yaşargil is Professor, Dr. Krisht is Associate Professor, Dr. Al-Mefty is Professor, Mrs. Yaşargil is Research Instructor, Department of Neurosurgery, University of Arkansas for Medical Sciences, 4301 West Markham, Slot #507, Little Rock, AR 72205; and Dr. Türe is Associate Professor, Department of Neurosurgery, Marmara University School of Medicine, Istanbul. The authors have disclosed that they have no significant relationships with or financial interests in any commercial organizations pertaining to this educational activity. Editor: Ali F. Krisht, M.D.* University of Arkansas for Medical Sciences Production Assistant: Ronalda Williams Editorial Board: Ossama Al-Mefty, M.D. Evandro De Oliveira, M.D. Curtis A. Dickman, M.D. Rudolph Fahlbusch, M.D. John Fox, M.D. Allan Friedman, M.D. Douglas Kondziolka, M.D. Mark Linskey, M.D. Tom Origitano, M.D. Glenn Pait, M.D. Kalmon Post, M.D. Chandra Sen, M.D. Robert Solomon, M.D. Martin Weiss, M.D. Gazi Yaçargil, M.D. * Dr. Krisht has disclosed that he has no significant relationships with or financial interests in any commercial organizations pertaining to this educational activity. Contemporary Neurosurgery: June 30th, 2002 - Volume 24 - Issue 13 - p 1-5 Buy Abstract Learning Objectives: After reading this article, the participant should be able to: Discuss the concepts of limbic and paralimbic gliomas. Determine the pathophysiologic and anatomic aspects of insular gliomas. Recall the clinical presentation and radiologic findings of insular gliomas. Question: A 35-year-old woman has been referred with the diagnosis of a deep-seated, inoperable, left-sided frontotemporal lesion. Can you comment on the radiologic findings and the possible diagnoses of this tumor? (Fig. 1)Figure 1.: T2-weighted axial MR image shows a left insular hyperintense lesion, which was hypointense on T1-weighted images and did not enhance with gadolinium. © 2002 Lippincott Williams & Wilkins, Inc.