Manoach Dara Sue Ph.D.; Sandson, Thomas A. M.D.; Weintraub, Sandra Ph.D.Neuropsychiatry, Neuropsychology & Behavioral Neurology: April 1995 ORIGINAL ARTICLE: PDF Only Abstract We report the findings of neurological examination, neurophysiological studies, and neuroimaging studies in two samples of patients with the social-emotional processing disorder (SEPD). The first sample was selected anecdotally, on the basis of having the clinical presentation and neuropsychological features of SEPD, as well as documented neurophysiological abnormalities. The second sample was selected by serial chart review, blind to neurodiagnostic findings, on the basis of neuropsychological profile and clinical presentation. SEPD is a developmental syndrome characterized by a history of markedly poor interpersonal adaptation and relative deficiencies in nonverbal cognitive ability and paralinguistic communication skills. The neurodiagnostic findings support the hypothesis that SEPD is associated with early brain injury that affects the right hemisphere and results in its failure to support the adequate development of the cognitive, affective, and behavioral functions it normally subserves. © Lippincott-Raven Publishers.