ORIGINAL ARTICLE: PDF OnlyDyskinesia Associated with Fluoxetine Use Case ReportFishbain, David A. M.SC, M.D., F.A.P.A*†§; Dominguez, M. M.D; Goldberg, Myron Ph.D†‡§; Olsen, E. M.D*; Rosomoff, Hubert M.D., D.MeD.Sc.†§ Author Information Departments of *Psychiatry, †Neurological Surgery, and ‡Psychology, University of Miami School of Medicine, Miami; §Comprehensive Pain and Rehabilitation Center at South Shore Hospital, and Department of Internal Medicine, South Shore Hospital, Miami Beach, Florida, U.S.A. Neuropsychiatry, Neuropsychology & Behavioral Neurology: April 1992 - Volume 5 - Issue 2 - p 97-100 Buy Abstract Although antidepressant-associated dyskinesia has been previously reported, this side effect has not been documented for fluoxetine, a selective inhibitor of presynaptic re-uptake of serotonin. Because of its clinical importance and its contribution to the understanding of the psychopharmacology of dyskinesia, such a case is described. The dyskinesia associated with antidepressants and also with fluoxetine appears to differ from that of neuroleptics. Antidepressants including fluoxetine may exacerbate rather than cause the pathophysiological process involved in the dyskinesia. © Lippincott-Raven Publishers.