GENDER MEDICINE, INFERTILITY AND ERECTILE FUNCTION: Edited by Ryan Flannigan and Ranjith RamasamyThe role of imaging in the diagnosis and management of Peyronie's diseaseParmar, Madhumitaa; Masterson, John M.b; Masterson, Thomas A. IIIa,cAuthor Information aDepartment of Urology, University of Miami, Miami, Florida bDepartment of Urology, Cedars-Sanai, Los Angeles, California cBruce W. Carter VA Medical Center, Division of Urology, Miami, Florida, USA Correspondence to Thomas A. Masterson III, MD, Bruce W. Carter VA Medical Center, Division of Urology, 1150 NW 14th St, Miami, FL 33136, USA. Tel: +1 305 243 4850; e-mail: Tmasterson@miami.edu Current Opinion in Urology: May 2020 - Volume 30 - Issue 3 - p 283-289 doi: 10.1097/MOU.0000000000000754 Buy Metrics Abstract Purpose of review Several imaging modalities exist for the assessment of Peyronie's disease. However, comprehensive recommendations for using these objective modalities based on large-scale evidence-based studies do not yet exist. Our objective is to evaluate current imaging techniques and provide a model that we follow in our clinic in the workup and management of Peyronie's disease. Recent findings Computed tomography and radiography excellently visualize penile plaque calcifications, and MRI adeptly identifies plaques in complex locations, such as the corporal septum. Ultrasonography has extensive applications in plaque localization and characterization. Used along with color Doppler ultrasound, it is capable of detecting vascular abnormalities. Sonoelastography is an emerging subtype of ultrasongraphy that utilizes elastic properties of tissue to identify penile plaques that may not be visualized with other modalities. Summary Ultrasonography is the preferred imaging modality in Peyronie's disease and noninvasively characterizes penile plaques and monitors plaque response to various treatments. At our center, we perform ultrasonography with intracavernosal injection in all patients with Peyronie's disease to evaluate the degree of curvature, plaque characteristics, and concomitant erectile dysfunction to better guide management decisions. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.