TESTOSTERONE REPLACEMENT THERAPY: HOW TO MAKE SENSE OF CONFLICTING ADVICE: Edited by Peter N. SchlegelTestosterone therapy improves erectile function and libido in hypogonadal menRizk, Paul J.a; Kohn, Taylor P.a; Pastuszak, Alexander W.b,c; Khera, MohitbAuthor Information aBaylor College of Medicine bScott Department of Urology cCenter for Reproductive Medicine, Baylor College of Medicine, Houston, Texas, USA Correspondence to Mohit Khera, MD, MBA, MPH, Scott Department of Urology, Baylor College of Medicine, 7200 Cambridge St., Houston, TX 77030, USA. Tel: +1 713 798 4001; e-mail: [email protected] Current Opinion in Urology: November 2017 - Volume 27 - Issue 6 - p 511-515 doi: 10.1097/MOU.0000000000000442 Buy Metrics Abstract Purpose of review Erectile dysfunction and decreased libido are common complaints in the older male population. Recent studies have elucidated the role testosterone therapy (TTh) can play in men with low testosterone levels. The aim of this review is to provide an overview of these findings and the utility of TTh. We specifically examine the role of TTh on erectile function, coadministration with phosphodiesterase type 5 inhibitors, and libido. Recent findings Recent publications suggest that TTh improves mild erectile dysfunction, though may be less useful in men with more severe erectile dysfunction. In men unresponsive to phosphodiesterase type 5 inhibitors and with mild erectile dysfunction, TTh can further improve erectile function. TTh has also shown consistent benefit in improving libido in men with low testosterone levels at baseline, with no additional improvements once testosterone levels are normalized. Summary The available literature supports a role for TTh in men with low testosterone levels, erectile dysfunction, and low libido, with symptomatic improvement in these men. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.