Varicocele repair for low testosteroneFisch, Harrya; Hyun, GracebCurrent Opinion in Urology: November 2012 - Volume 22 - Issue 6 - p 495–498 doi: 10.1097/MOU.0b013e328358e0fb VARICOCELE: STANDARD AND ALTERNATIVE INDICATIONS FOR REPAIR: Edited by Peter N. Schlegel Buy Abstract Author InformationAuthors Article MetricsMetrics Purpose of review Several recent clinical studies have added to the existing literature on the impact of varicocelectomy on serum testosterone levels. These studies were not included in the most recent previous review of this topic and strengthen considerably the evidence base supporting the claim that varicocele repair can reliably restore below-normal testosterone levels. Recent findings Three studies were published in 2011 on the effect of varicocele repair on testosterone levels. These studies were all adequately powered to detect statistically significant changes in testosterone preprocedure and postprocedure, and all demonstrated significant increases in testosterone levels in patients who had low preprocedure testosterone levels. Summary Varicocele repair can restore testosterone to the eugonadal range in hypogonadal patients with either unilateral or bilateral varicocele. aWeill Cornell Medical College/New York Presbyterian Hospital bPediatric Urology, Mount Sinai Medical School, New York, New York, USA Correspondence to Harry Fisch, MD, FACS, Clinical Professor of Urology and Reproductive Medicine, Weill Cornell medical College/New York Presbyterian Hospital, 944 Park Avenue, New York, NY 10028, USA. Tel: +1 212 879 0800; e-mail: HarryFisch@aol.com © 2012 Lippincott Williams & Wilkins, Inc.