REVIEWDelayed graft function: current status and future directionsSwanson, Kurtis J.a; Bhattarai, Manojb; Parajuli, Sandesha Author Information aDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin bDivision of Nephrology, Department of Medicine, University of Texas San Antonio, San Antonio, Texas, USA Correspondence to Sandesh Parajuli, MD, Department of Medicine, Division of Nephrology, University of Wisconsin School of Medicine and Public Health, 4175 MFCB, 600 Highland Ave, Madison, WI 53705, USA. E-mail: [email protected] Current Opinion in Organ Transplantation: November 08, 2022 - Volume - Issue - 10.1097/MOT.0000000000001034 doi: 10.1097/MOT.0000000000001034 Buy PAP Metrics Abstract Purpose of review Delayed graft function is a common early posttransplant event predictive of adverse outcomes including hospital readmission, impaired long-term graft function, and decreased graft and patient survival. The purpose of this review is to summarize recent literature describing delayed graft function in hopes of better understanding and managing this condition. Recent findings Recent research efforts have been garnered towards risk factor modification, prevention, and earlier detection of delayed graft function. In this review, we aim to summarize current innovative approaches and future directions. Summary Delayed graft function portends worse graft and patient outcomes. Continued research to prevent, and detect early perturbations in allograft function, and more optimally manage this disease will hopefully improve graft function, along with graft/patient survival. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.