REVIEWAddressing sex-based disparities in liver transplantationHundt, Melanie A.a,b; Tien, Christineb; Kahn, Jeffrey A.a,b Author Information aDivision of Gastrointestinal and Liver Diseases bDepartment of Medicine, University of Southern California, Los Angeles, California, USA Correspondence to Jeffrey A. Kahn, MD, Professor of Clinical Medicine, Medical Director of Liver Transplantation, University of Southern California, 1510 San Pablo Street, Suite 255, Los Angeles, CA 90033, USA. Tel: +1 323 442 5908; e-mail: [email protected] Current Opinion in Organ Transplantation ():10.1097/MOT.0000000000001040, November 25, 2022. | DOI: 10.1097/MOT.0000000000001040 Buy PAP Metrics Abstract Purpose of review Disparities in access to liver transplantation by sex have been well described, disadvantaging women. Understanding the multifactorial causes of these disparities as well as the variety of proposed solutions is critical to improving access to this life-saving intervention for women. This review aims to summarize the current body of evidence on observed sex disparities in liver transplantation and highlight actionable, evidence-based mechanisms by which these disparities can be addressed. Recent findings Strategies for addressing sex disparities in liver transplantation include increasing organ utilization, changing allocation policy, and leveraging public policies to reduce the incidence of end-stage liver disease. Several other promising interventions are currently being explored. Summary In the United States, women face additional barriers to liver transplantation on the basis of sex. Immediate action is necessary to systematically address these inequities. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.