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Pediatric lung transplantation

supply and demand

Benoit, Tobias M.a; Benden, Christianb

Current Opinion in Organ Transplantation: June 2019 - Volume 24 - Issue 3 - p 324–328
doi: 10.1097/MOT.0000000000000630
LUNG TRANSPLANTATION: Edited by Allan R. Glanville

Purpose of review Lung transplantation has become an accepted therapy in infants, children, and adolescents suffering from end-stage lung diseases, an impaired quality of life and reduced life expectancy. The aim of this review is to highlight specific aspects of pediatric lung transplantation and to give an update on recent findings.

Recent findings Currently, over 100 lung transplant procedures are performed in children annually worldwide. Long-term success is limited by availability of donor organs and waitlist mortality pretransplant, and an increased infection risk because of immunosuppression, and most importantly late complications, such as chronic lung allograft dysfunction, medication nonadherence, and transition intricacies.

Summary Specific aspects of pediatric lung transplantation will be reviewed and an update on most recent developments in the management of pediatric lung transplant recipients given.

aDivision of Internal Medicine

bDivision of Pulmonary Medicine, University Hospital Zurich, Zurich, Switzerland

Correspondence to Christian Benden, MD FCCP, Medical Director of Lung Transplantation, Division of Pulmonary Medicine, University Hospital Zurich, CH-8091 Zurich, Switzerland. Tel: +41 44 255 41 83; e-mail:

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