CANCER-RELATED COGNITIVE IMPAIRMENT: Beyond ‘Chemofog’: CRCI due to radiation and hormone therapies: Edited by Janet Ellis and Elie Isenberg-GrzedaCognitive impairment following hormone therapy: current opinion of research in breast and prostate cancer patientsWu, Lisa M.a,∗; Amidi, Alib,c,∗Author Information aDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA bUnit for Psycho-oncology and Health Psychology, Department of Oncology, Aarhus University Hospital cDepartment of Psychology, Aarhus University, Aarhus, Denmark Correspondence to Lisa M. Wu, Ph.D., Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, 633 North St. Clair – Suite 19–000, Chicago, IL 60657, USA. Tel: +1 312 503 7722; e-mail: [email protected] Current Opinion in Supportive and Palliative Care: March 2017 - Volume 11 - Issue 1 - p 38-45 doi: 10.1097/SPC.0000000000000251 Buy Metrics Abstract Purpose of review Hormone therapy is a common cancer treatment that may be associated with numerous side and late effects, and in recent years, has been linked to changes in cognition. Here, we present the most important recent findings from empirical studies and reviews that have focused on the effects of hormone therapy on cognitive functioning in breast and prostate cancer populations, underline some general shortcomings, and propose directions for future research. Recent findings Recent research indicates that cognitive impairment may occur in breast and prostate cancer patients following onset of hormone therapy. However, because of methodological shortcomings and heterogeneity of current research, conclusions regarding the effects of hormone therapy on cognitive functions remain tentative. Summary The review highlights the general findings while also describing the many methodological shortcomings that need to be addressed in future research. It is clear that larger scale neuropsychological studies that also evaluate the impact of impairments on daily life functioning will improve our understanding of the effects of hormone therapy on cognition and inform the development of appropriate interventions. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.