Combined qualitative and quantitative research designsSeymour, JaneCurrent Opinion in Supportive and Palliative Care: December 2012 - Volume 6 - Issue 4 - p 514–524 doi: 10.1097/SPC.0b013e328358214e CHALLENGES IN CONDUCTING CLINICAL TRIALS IN SUPPORTIVE AND PALLIATIVE CARE: Edited by Amy P. Abernethy, Deborah W. Bruner and David C. Currow Buy Abstract Author InformationAuthors Article MetricsMetrics Purpose of review Mixed methods research designs have been recognized as important in addressing complexity and are recommended particularly in the development and evaluation of complex interventions. This article reports a review of studies in palliative care published between 2010 and March 2012 that combine qualitative and quantitative approaches. Recent findings A synthesis of approaches to mixed methods research taken in 28 examples of published research studies of relevance to palliative and supportive care is provided, using a typology based on a classic categorization put forward in 1992. Summary Mixed-method studies are becoming more frequently employed in palliative care research and resonate with the complexity of the palliative care endeavour. Undertaking mixed methods research requires a sophisticated understanding of the research process and recognition of some of the underlying complexities encountered when working with different traditions and perspectives on issues of: sampling, validity, reliability and rigour, different sources of data and different data collection and analysis techniques. Queen's Medical Centre, School of Nursing, Midwifery and Physiotherapy, University of Nottingham, Nottingham, UK Correspondence to Jane Seymour, Sue Ryder Care Professor in Palliative and End of Life Studies, School of Nursing, Midwifery and Physiotherapy, Queen's Medical Centre, Derby Road, University of Nottingham, NG7 2HA, UK. Tel: +44 0 115 8231202; e-mail: email@example.com © 2012 Lippincott Williams & Wilkins, Inc.