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The role of rehabilitation in patients with pulmonary arterial hypertension

Eichstaedt, Christina A.a,b,c; Benjamin, Nicolaa,b; Xanthouli, Panagiotaa,b; Marra, Alberto M.d; Grünig, Ekkeharda,b

Current Opinion in Pulmonary Medicine: September 2019 - Volume 25 - Issue 5 - p 398–404
doi: 10.1097/MCP.0000000000000609
DISORDERS OF THE PULMONARY CIRCULATION: Edited by Richard Channick and Anton Vonk Noordegraaf

Purpose of review The current review summarizes the latest evidence of the effects of exercise training for pulmonary hypertension patients demonstrated by six randomized controlled trails and 20 further studies. As the availability of exercise training is still limited it is important to raise awareness of the body of evidence showing the benefit for the patients and the limitations.

Recent findings The effects of exercise training on exercise capacity, hemodynamics as well as quality of life are described as well as different settings and components of exercise training. Associated adverse events are critically reviewed and strategies for avoidance of these events discussed. Lastly, the most important issues of availability and reimbursement of a specialized exercise training program are examined and the future path is outlined to improve patient access.

Summary The latest publications on this topic strengthen the call for international multicenter randomized controlled trials to establish the feasibility of exercise training in different healthcare systems and to enhance patient access to these programs.

aCentre for Pulmonary Hypertension, Thoraxklinik at Heidelberg University Hospital

bTranslational Lung Research Center Heidelberg (TLRC), Member of the German Center for Lung Research (DZL)

cInstitute of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany

dIRCCS SDN, Research Institute, Naples, Italy

Correspondence to Ekkehard Grünig, Prof Dr, Centre for Pulmonary Hypertension, Thoraxklinik at Heidelberg University Hospital, Röntgenstraße 1, 69126 Heidelberg, Germany. Tel: +49 6221 396 8076; fax: +49 6221 396 1209; e-mail:

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