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Nonresolving pneumonia in the setting of malignancy

Arab, Talal; Malekzadegan, Mohammad R.; Morante, Joaquin; Cervellione, Kelly L.; Fein, Alan M.

Current Opinion in Pulmonary Medicine: July 2019 - Volume 25 - Issue 4 - p 331–335
doi: 10.1097/MCP.0000000000000588
NEOPLASMS OF THE LUNG WITH IMAGING: Edited by Alan M. Fein and David E. Ost

Purpose of review This article reviews recent literature and experience in the diagnosis of nonresolving and slowly resolving pneumonia as it pertains to malignancy.

Recent findings Malignancy must be considered as an important cause of pneumonia that resolves slowly or has incomplete resolution. Airway obstruction is more common than malignant infiltration as a cause of pneumonia that does not resolve appropriately. Infection due to resistant or unusual organisms must also be considered in the differential diagnosis.

Summary Nonresolving pneumonia remains an important clinical challenge. Bronchoscopic evaluation in conjunction with computed tomography and PET scanning is still the most important technique for diagnosis.

Pulmonary, Critical Care and Sleep Medicine, Prohealthcare Association LLP, Lake Success, New York, USA

Correspondence to Alan M. Fein, MD, Pulmonary, Critical Care and Sleep Medicine, Prohealthcare Association LLP, 1 Dakota Drive, Suite 202, Lake Success, NY 11042, USA. Tel: +1 516 608 2890; fax: +1 718 206 5805; e-mail:

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