Obstructive, occupational, and environmental diseasesRespiratory effects of long-term exposure to cotton dustChristiani, David C. MD, MPH, MS; Wang, Xiao-Rong MD, PhD Author Information *Department of Environmental Health (Occupational Health Program), Harvard School of Public Health; †Pulmonary and Critical Care Unit, Massachusetts General Hospital, Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA. Supported by the National Institute for Occupational Safety and Health (grant no. OH2421) and the National Institutes of Health (grant no. ES00002). Correspondence to David C. Christiani, MD, MPH, MS, Occupational Health Program, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA; e-mail: [email protected] Current Opinion in Pulmonary Medicine: March 2003 - Volume 9 - Issue 2 - p 151-155 Buy Abstract Traditionally, the concept of cotton dust-related disease focused on acute airway responses. A possible connection of long-term exposure to cotton dust with chronic obstructive airway disease was not addressed until the past two decades. This review summarizes the latest findings relevant to this topic that were observed from longitudinal cohort studies and discusses the relation between acute airway responses and chronic losses of lung function. Copyright © 2003 Wolters Kluwer Health, Inc. All rights reserved.