Review ArticleMedication and non-medication treatments of post-traumatic stress disorderBryant, Richard A.a; Friedman, Matthewb,c,Author Information aUniversity of New South Wales, Sydney, Australia; bNational Center for PTSD, White River Junction, Vermont, USA; and cDartmouth Medical School, Hanover, New Hampshire, USA Correspondence to Richard A. Bryant, School of Psychology, University of New South Wales, NSW 2052, Australia. Tel: +61 2 93853640; fax: +61 2 93853641; e-mail: [email protected] Abbreviations ASD: acute stress disorder CBT: cognitive behavior therapy CT: cognitive therapy EMDR: eye movement desensitization and reprocessing FDA: US Food and Drug Administration PE: prolonged exposure PTSD: post-traumatic stress disorder SC: supportive counselling SIT: stress inoculation training SSRI: selective serotonin re-uptake inhibitor Current Opinion in Psychiatry: March 2001 - Volume 14 - Issue 2 - p 119-123 Buy Abstract Recent developments in the psychological and pharmacological management of post-traumatic stress disorder are reviewed. This review of controlled outcome studies indicates that: (i) cognitive behavior therapy is the psychological treatment of choice; (ii) different components of cognitive behavior therapy can be effective; (iii) eye movement desensitization and reprocessing is not as effective as cognitive behavior therapy; (iv) selective serotonin re-uptake inhibitors are the pharmacological treatment of choice; and (v) there is increasing support for nefazadone but not for cyproheptadine in reducing the symptoms of post-traumatic stress disorder. The need for increased treatment effectiveness and the integration of recent findings into clinical practice is discussed. © 2001 Lippincott Williams & Wilkins, Inc.