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Editorial introductions

Editor(s): Bernstein, Daniel; Wyllie, Robert; Bernstein, Henry H.

Current Opinion in Pediatrics: October 2017 - Volume 29 - Issue 5 - p v-vii
doi: 10.1097/MOP.0000000000000540
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Current Opinion in Pediatrics was launched in 1989. It is one of a successful series of review journals whose unique format is designed to provide a systematic and critical assessment of the literature as presented in the many primary journals. The field of pediatrics is divided into 18 sections that are reviewed once a year. Each section is assigned a Section Editor, a leading authority in the area, who identifies the most important topics at that time. In addition to this, Henry H. Bernstein also invites a prominent authority in the field of Office Pediatrics to write on the subject for each issue. Here we are pleased to introduce the Section Editors for this issue.


Daniel Bernstein

Daniel Bernstein

Dr Daniel Bernstein received his undergraduate degree in biology at MIT and attended medical school at New York University, USA. He completed his residency at Montefiore Medical Center in New York, spent a year as a fellow in medical education at Albert Einstein College of Medicine, and then a fellowship in pediatric cardiology at UC San Francisco, USA. Dr Bernstein joined the faculty at Stanford in 1986, where he is now the Alfred Woodley Salter and Mabel G. Salter Endowed Professor of Pediatrics. He served as Chief of Pediatric Cardiology for 18 years, and Director of the Children's Heart Center at Lucile Packard Children's Hospital at Stanford.

Dr Bernstein has maintained a general pediatric cardiology practice since his first years at Stanford and has also been at the forefront of pediatric heart failure and transplantation since the infancy of both fields. He established Stanford's first transplant clinic for children and published some of the first descriptions of growth in the transplanted heart, post-transplant lymphoma (PTLD), and transplantation for congenital heart disease. He is currently co-investigator on Stanford's NIH-funded clinical trial on biomarkers for post-transplant lymphoproliferative disorders in children.

Dr Bernstein has directed an NIH- and AHA-funded basic science lab for over 25 years, focusing on the role of cell surface receptors in modulating cardiotoxicity and cardioprotection. He was part of the collaborative team that created some of the first gene knockouts. His recent work has focused on the connection between ß-adrenergic receptors and mitochondrial function, and on the molecular mechanisms of RV failure, a critical issue for children with congenital heart disease. He is now applying the powerful new platform of patient-derived induced pluripotent stem cells (iPSCs) to study the mechanisms of pediatric cardiac diseases and to enhance the power of pharmacogenomics to screen patients for susceptibility to drug toxicity, e.g. the anthracycline anti-cancer agent, doxorubicin.

Dr Bernstein has published over 170 peer-reviewed articles, has authored the Cardiovascular chapter of Nelson's Textbook of Pediatrics, and is the Editor of Pediatrics for Medical Students, the first textbook written specifically to enhance critical thinking skills for students during the Pediatrics clinical clerkship.

Robert Wyllie

Robert Wyllie

Robert Wyllie, MD, has been the Chief of Medical Operations at Cleveland Clinic, USA, since 2011. In this position he is responsible for the activities of a variety of units including Business Intelligence, Pharmacy, Continuous Improvement, Hospital Throughput, Surgical Operations, Critical Care Transport and management of post-acute patient services. Dr Wyllie also has been active in driving down the cost of health care while improving quality and enhancing patient experience.

Cleveland Clinic is a world leader in hospital transfers, with nearly 2,500 transfers per month from 48 states and 22 countries. Cleveland Clinic's Main Campus is among the largest and busiest hospitals in the United States, with 55,000 admissions in 2016. As a large academic medical centers, Cleveland Clinic's surgical operations are ranked among the most efficient in the United States, with 80% utilization. Cleveland Clinic has been recognized by the University Hospital Consortium for its outstanding work in quality and efficiency, winning an awards as the Most Improved Hospital among academic medical centers. To discuss these activities and accomplishments, Dr Wyllie is invited to the World Conference of Health Care and other venues.

Before Cleveland Clinic's President and CEO, Dr Delos Cosgrove, brought him onto his Executive Team, Dr Wyllie was Chief of Cleveland Clinic Children's Hospital, Chairman of the Pediatric Institute, and the first holder of the Calabrese Endowed Chair in Pediatrics. During his five years in the position, Dr Wyllie recruited 160 physicians and tripled the number of pediatricians and pediatric subspecialists at Cleveland Clinic. Under his leadership, every pediatric specialty became ranked nationally by US News & World Report, and Cleveland Clinic's became the highest rated Children's Hospital in northern Ohio. Dr Wyllie built a system for pediatric care across northeast Ohio, with three level 3 neonatal intensive care units staffed 24/7 by pediatric neonatologists and community hospitals staffed at all times by on-site pediatricians. Under Dr Wyllie's leadership, Cleveland Clinic's Children's Hospital grew to be the largest provider of pediatric services in northeast Ohio.

Dr Wyllie is also a world renowned pediatric gastroenterologist with subspecialty interest in inflammatory bowel disease and complex endoscopic procedures. He is Board Certified in pediatrics and pediatric gastroenterology and nutrition, and has been repeatedly named among Castle Connolly's America's Top Doctors, Best Doctors in America, and Consumers’ Checkbook Guide to Top Doctors. His other prominent roles at Cleveland Clinic include Member of the Board of Governors, Vice Chair of the Office of Professional Staff Affairs, and Past President of the Professional Staff.

Dr Wyllie is a member of the American Society of Gastrointestinal Endoscopy, the American College of Gastroenterology, the American Gastroenterological Association, the North American Society of Pediatric Gastroenterology, Hepatology, and Nutrition, the American Academy of Pediatrics, and the Crohn's and Colitis Foundation of America. He is editor of a major textbook in pediatric gastroenterology, starting on its sixth edition, and has authored over 130 articles in scientific journals including New England Journal of Medicine, Pediatrics, Journal of Pediatrics, Clinical Pediatrics, Emergency Medicine, American Family Physician, Journal of Nuclear Medicine, Hepatology, and the American Academy of Pediatrics update. He has presented at more than 185 national and international scientific meetings and has delivered more than 135 presentations at hospitals and medical centers.

Dr Wyllie graduated with honors from the Indiana University School of Medicine, where he also completed a residency in pediatrics and a fellowship in pediatric gastroenterology and nutrition. Dr Wyllie earned membership in Phi Beta Kappa while pursuing his undergraduate degree at Indiana University and received the Lyman Mieks Award as the outstanding student in pediatrics. His wife, Dr Elaine Wyllie, is a world renowned pediatric epileptologist at Cleveland Clinic, and their two sons are pursuing exciting careers in science and technology.

Henry H. Bernstein

Henry H. Bernstein

Dr Bernstein is a Professor of pediatrics at Hofstra Northwell School of Medicine in New York, USA. He taps into his extensive 32-year experience as a general pediatrician in private practice and in academia at urban, suburban, and rural children's hospitals to promote the health and wellbeing of children, their families, and their communities. His private, community-based primary care (generalist) experiences in combination with academic experiences have provided him with a value-added, translational science perspective, unique from many others in academia. This tacit knowledge enables him to fulfill a lifelong passion of communicating, educating, and translating science into clinical settings, educational venues, policy-making, and media interactions to advance the health of children.

Research is consistently woven into the fabric of Dr Bernstein's clinical practice, which has served as a “laboratory” for his active studies. His research and quality improvement initiatives focus on issues important to Academic General Pediatrics and community-based practice, including immunizations, postpartum newborn discharge, childhood obesity, breastfeeding, health promotion, preventive health screening in primary care, technology, and medical education. His commitment, innovative spirit, and enthusiasm also encompass many facets of medical education along the continuum, from training and mentoring future physicians to fostering lifelong learning, to supporting the continuous professional development of practicing pediatricians.

Hank is an ex-officio member of the American Academy of Pediatrics’ Committee on Infectious Diseases (Red Book Committee), Associate Editor of Red Book Online (, and AAP liaison to the CDC Advisory Committee on Immunization Practices’ Influenza Workgroup, spearheading both seasonal and pandemic influenza preparedness and policy for children. In addition, he is Editor-in-Chief Emeritus of PediaLink (, the AAP's online home for lifelong learning and chair of the interdisciplinary Bright Futures Health Promotion Workgroup, which has created a distinctive health promotion curriculum, videos, and a companion educational website ( He regularly shares his knowledge and expertise by educating the public, writing for health information websites, and participating in media interviews on a variety of pediatric health care issues including immunization, diagnosis and treatment of common childhood infectious diseases and illnesses, and practical information for parents, teachers and caregivers.

In the spirit of lifelong learning, Hank earned a Masters in Healthcare Management (MHCM) at Harvard School of Public Health in 2013. He actively maintains his certification by the American Board of Pediatrics. He completed his residency training in Pediatrics at St. Christopher's Hospital for Children in Philadelphia, after earning his medical degree from the University of Medicine and Dentistry of New Jersey - School of Osteopathic Medicine, USA. Hank and his wife, Sophie, have been married for 36 years and are extremely proud of their 31-year-old daughter, Lauren, and 26-year-old son, David.

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