PULMONOLOGY: Edited by David N. CornfieldManifestations of pulmonary aspergillosis in pediatricsChacko, Archanaa; Moss, Richard B.bAuthor Information aQueensland Respiratory and Sleep Department, Queensland Children's Hospital, Brisbane, Queensland, Australia bDepartment of Pediatrics, Center for Excellence in Pulmonary Biology, Stanford University School of Medicine, Palo Alto, California, USA Correspondence to Archana Chacko, Queensland Respiratory and Sleep Department, Queensland Children's Hospital, 501 Stanley Street, Brisbane, Qld 4101, Australia. Tel: +61 7 3162 0377; fax: +61 7 3162 3221; e-mail: firstname.lastname@example.org Current Opinion in Pediatrics: June 2020 - Volume 32 - Issue 3 - p 389-394 doi: 10.1097/MOP.0000000000000898 Buy Metrics Abstract Purpose of review Aspergillus spp. cause a clinical spectrum of disease with severity of disease dependent on degree of immune compromise, nature and intensity of inflammatory host response, and/or underlying lung disease. Chronic pulmonary aspergillosis encompasses a spectrum of diseases including aspergilloma, Aspergillus nodules, chronic cavitary pulmonary aspergillosis, chronic fibrosing pulmonary aspergillosis, and subacute invasive pulmonary aspergillosis. Allergic bronchopulmonary aspergillosis (ABPA) paradoxically is an immune hypersensitivity manifestation in the lungs that almost always occurs in the setting of underlying asthma or cystic fibrosis. These chronic Aspergillus conditions are now becoming more prevalent than invasive Aspergillus, thus it is important to be aware of the current literature of these conditions. Recent findings High-level research assessing the clinical significance and treatment options of these chronic diseases are lacking. Recent literature suggests colonization is antecedent for local airway infection (Aspergillus bronchitis), chronic or allergic bronchopulmonary disease, or invasive and potentially disseminated disease. There have been few advances in assessment of treatment of ABPA. Summary Research assessing the clinical significance and treatment options is currently needed. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.