ENDOCRINOLOGY AND METABOLISM: Edited by Sally RadovickDiagnosis and management of hypopituitarismYeliosof, Olga; Gangat, Mariam Author Information Pediatric Endocrinology, Rutgers-Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA Correspondence to Olga Yeliosof, MD, Fellow, Pediatric Endocrinology, Rutgers-Robert Wood Johnson Medical School, Child Health Institute of New Jersey, Rutgers, The State University of New Jersey, 89 French Street, New Brunswick, NJ 08901, USA. Tel: +1 732 235 9378; e-mail: [email protected] Current Opinion in Pediatrics: August 2019 - Volume 31 - Issue 4 - p 531-536 doi: 10.1097/MOP.0000000000000779 Buy Metrics Abstract Purpose of review This review summarizes pituitary function, and the clinical presentation and treatment of hypopituitarism. Recent findings Updates in the field include new guidelines and meta-analyses on the diagnosis and treatment of select hormone deficiencies, novel treatment options, and advances in next generation sequencing technology. Summary Hypopituitarism is defined as partial or complete loss of a single or multiple pituitary hormones. The clinical presentation of hypopituitarism varies depending on the number and severity of hormone deficiencies. Treatment involves the physiologic replacement of the individual end-organ hormone deficiencies and requires close lifelong monitoring. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.