SURGERY: Edited by Brad W. WarnerNonoperative management of appendicitis in childrenLópez, Joseph J.a,b; Deans, Katherine J.a,c; Minneci, Peter C.a,cAuthor Information aCenter for Surgical Outcomes Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio bDepartment of Surgery, New York Medical College-Westchester Medical Center, Valhalla, New York cDepartment of Pediatric Surgery, Nationwide Children's Hospital, Columbus, Ohio, USA Correspondence to Peter C. Minneci, MD, MHSc, Center for Surgical Outcomes Research, The Research Institute at Nationwide Children's Hospital, 611 Livingston Ave, Faculty Office Building, Suite 3, Columbus, OH 43205, USA. Tel: +1 614 722-5922; fax: +1 614 722 3544; e-mail: Peter.Minneci@nationwidechildrens.org Current Opinion in Pediatrics: June 2017 - Volume 29 - Issue 3 - p 358-362 doi: 10.1097/MOP.0000000000000487 Buy Metrics Abstract Purpose of review The aim of this review is to summarize the recent literature investigating nonoperative management of uncomplicated and complicated appendicitis and highlight recent data establishing its safety and efficacy. Recent findings Recent studies and clinical trials have demonstrated the efficacy of nonoperative treatment of both uncomplicated and complicated appendicitis, defined as perforated appendicitis with or without formed abscess or phlegmon. Nonoperative management of uncomplicated appendicitis has been reported to be effective in approximately 71–94% of cases. In complicated appendicitis, treatment with antibiotics alone or antibiotics with interval appendectomy has been shown to be a well tolerated and reasonable treatment alternative. Summary Appendicitis is one of the most common surgical diagnoses in children. The standard of care for many years has been surgical appendectomy; however, it carries with it risks including bleeding, wound complications, injury to surrounding structures, and the potential need for reoperation. Nonoperative management of both uncomplicated and complicated appendicitis in children is well tolerated and efficacious in select populations. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.