SURGERY: Edited by Brad W. WarnerCentral venous access in children: indications, devices, and risksAres, Guillermo; Hunter, Catherine J.Author Information Division of Pediatric Surgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA Correspondence to Catherine J. Hunter, Division of Pediatric Surgery, Ann and Robert H. Lurie Children's Hospital of Chicago, 225 E Chicago Ave, Box 63, Chicago, IL 60611, USA. Tel: +1 312 227 4210; e-mail: firstname.lastname@example.org Current Opinion in Pediatrics: June 2017 - Volume 29 - Issue 3 - p 340-346 doi: 10.1097/MOP.0000000000000485 Buy Metrics Abstract Purpose of review Central venous catheters (CVCs) have a prominent role in the diagnostic and therapy of neonates and children. Herein, we describe the multiple indications for CVC use and the different devices available for central venous access. Given the prevalent use of CVCs, healthcare systems are focused on reducing complications from their use, particularly central line-associated bloodstream infections (CLABSIs). The most up-to-date information available sheds light on best practices and future areas of investigation. Recent findings Large systematic reviews of randomized trials suggest that ultrasound guidance for placement of CVCs in children is safer than using blind technique, at least for internal jugular vein access. Appropriate catheter tip placement is associated with decreased complications. Furthermore, the prophylactic use of ethanol lock between cycles of parenteral nutrition administration has reduced the rates of CLABSI. A recent randomized trial in pediatric CVCs showed a benefit with antibiotic-coated CVCs. Summary Based on the available evidence, multiple techniques for CVC placement are still valid, including the landmark technique based on practitioner experience, but ultrasound guidance has been shown to decrease complications from line placement. Adherence to CVC care protocols is essential in reducing infectious complications. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.