Great strides in the identification, etiologic understanding, and treatment of metabolic and genetic disorders associated with infantile seizures have occurred in recent years. We explain the cause, pathogenesis, diagnosis, presentation, and treatment of certain metabolic disorders that now have defined interventions that improve and optimize neurologic outcome. A systematic approach to infantile seizures will allow the primary practitioner to more effectively create a differential diagnosis with close attention to the disorders that have specific treatment applications.
aDepartment of Clinical Sciences, Florida State University College of Medicine, Tallahassee, Florida
bSection of Clinical Genetics and Metabolism, Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colorado, USA
Correspondence to Lea K. Parsley, MD, Department of Clinical Sciences, Florida State University College of Medicine, 1115 West Call St, Tallahassee, Florida, USA Tel: +1 850 645 1781; e-mail: firstname.lastname@example.org