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Re-evaluation of antibiotic treatment of streptococcal pharyngitis

Baltimore, Robert S

doi: 10.1097/MOP.0b013e32833502e7
Infectious diseases and immunization: Edited by Robert S. Baltimore and Hal B. Jenson

Purpose of review Recently, recommendations from the American Heart Association regarding treatment of streptococcal tonsillo-pharyngitis were revised. This review provides the background for changes that were made in comparison with the group's 1995 recommendations. Recent papers on other issues relating to group A Streptococcus are also reviewed.

Recent findings For antibiotic treatment of streptococcal tonsillopharyngitis the recommendations for injectable penicillin and for oral erythromycin are downgraded. First choice remains penicillin V but there is increasing acceptance of once-daily amoxicillin.

Conclusion Streptococcal pharyngitis is still a major infectious disease seen in pediatric office practice. The main job of the practitioner is to make an accurate diagnosis and provide appropriate treatment in timely fashion in order to prevent acute rheumatic fever.

Professor of Pediatrics and Epidemiology, Yale University School of Medicine, New Haven, Connecticut, USA

Correspondence to Robert S. Baltimore, MD, Department of Pediatrics, Yale University School of Medicine, Box 208064, 333 Cedar Street, New Haven, CT 06520-8064, USA Tel: +1 203 785 4655; fax: +1 203 785 7194; e-mail:

© 2010 Lippincott Williams & Wilkins, Inc.