Evaluation and treatment of isolated sphenoid sinus diseasesTang, Ing Pinga; Brand, Yvesb; Prepageran, NarayananbCurrent Opinion in Otolaryngology & Head and Neck Surgery: February 2016 - Volume 24 - Issue 1 - p 43–49 doi: 10.1097/MOO.0000000000000218 NOSE AND PARANASAL SINUSES: Edited by Samuel S. Becker and Nithin D. Adappa Buy Abstract Author InformationAuthors Article MetricsMetrics Purpose of review To review cause, clinical evaluation, medical and surgical management of isolated sphenoid sinus diseases. Recent findings Early diagnosis of isolated sphenoid sinus diseases requires a high index of clinical suspicion and appropriate radiological imaging. Sphenoid sinus can be approached endoscopically via a few different surgical techniques. Summary Isolated sphenoid sinus diseases are uncommon, with nonspecific clinical presentation. Early diagnosis requires a high index of clinical suspicion, proper endoscopic nasal examination, and appropriate radiological imaging. Surgical intervention is the primary treatment modality for most of the isolated sphenoid sinus diseases. Endoscopic endonasal approach to sphenoid sinus is the technique of choice. The location of sphenoid sinus disease, the extent of the surgery, and anatomic configuration of the sphenoid sinus are the main factors that help to decide the most suitable surgical approach to the sphenoid sinus. aDepartment of Otorhinolaryngology, Faculty of Medicine, University Malaysia Sarawak, Kota Samarahan, Sarawak bDepartment of Otorhinolaryngology, University Malaya Medical Centre, University of Malaya, Kuala Lumpur, Selangor, Malaysia Correspondence to Narayanan Prepageran, Professor, Department of Otolaryngology – Head and Neck Surgery, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. Tel: +60126281537; fax: +60379556963; e-mail: email@example.com;firstname.lastname@example.org Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.