Institutional members access full text with Ovid®

Share this article on:

Laryngeal cancer

Tomeh, Chafeek; Holsinger, F. Christopher

Current Opinion in Otolaryngology & Head and Neck Surgery: April 2014 - Volume 22 - Issue 2 - p 147–153
doi: 10.1097/MOO.0000000000000032
HEAD AND NECK ONCOLOGY: Edited by Piero Nicolai and Cesare Piazza

Purpose of review Treatment of laryngeal carcinoma continues to evolve, and whereas there was a transition from total laryngectomy to chemoradiation in response to the Veterans Affairs study and Radiation Therapy Oncology Group (RTOG) 91–11, recent data suggest the role of partial laryngectomy must be revisited.

Recent findings Recent data have shown that laryngeal preservation does not equate with laryngeal function. Data are accumulating in support of operative management of advanced laryngeal carcinoma away from chemoradiation for select patients. In particular, supracricoid laryngectomy may be a viable option for intermediate and selected advanced laryngeal carcinoma while maintaining laryngeal function.

Summary The evolution of treatment for advanced laryngeal carcinoma is focusing treatment on maintaining locoregional control while also maintaining a functional larynx.

Division of Head and Neck Surgery, Department of Otolaryngology, Stanford University, Palo Alto, California, USA

Correspondence to F. Christopher Holsinger, MD, FACS, Professor, Department of Otolaryngology, Chief, Division of Head and Neck Surgery, Stanford University School of Medicine, 875 Blake Wilbur Drive, CC-2227, Palo Alto, CA 94304-2205, USA. Tel: +1 650 725 6985; fax: +1 650 725 8502; e-mail:

© 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins