Laryngology and bronchoesophagology: Edited by Peter C. BelafskyLaryngeal reinnervation for bilateral vocal fold paralysisMarina, Mat B.a,b,d; Marie, Jean-Paulc; Birchall, Martin A.a,bAuthor Information aRoyal National Throat Nose and Ear Hospital bEar Institute, University College London, London, UK cDepartment of Otolaryngology Head and Neck Surgery, Rouen University Hospital, and Experimental Surgical Laboratory, EA 3830 GRHV, University of Rouen, France dFaculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia Correspondence to Martin Anthony Birchall, Professor of Laryngology, Professorial Unit, Royal National Throat Nose and Ear Hospital, 330 Gray's Inn Road, London WC1X 8DA, UKTel: +44 207 915 1308; e-mail: [email protected] Current Opinion in Otolaryngology & Head and Neck Surgery: December 2011 - Volume 19 - Issue 6 - p 434-438 doi: 10.1097/MOO.0b013e32834c7d30 Buy Metrics Abstract Purpose of review Laryngeal reinnervation for bilateral vocal fold paralysis (BVFP) patients is a promising technique to achieve good airway, although preserving a good quality of voice. On the other hand, the procedure is not simple. This review explores the recent literature on surgical technique and factors that may contribute to the success. Recent findings Research and literature in this area are limited due to variability and complexity of the nerve supply. The posterior cricoarytenoid (PCA) muscle also receives nerve supply from the interarytenoid branch. Transection of this nerve at the point between interarytenoid and PCA branch may prevent aberrant reinnervation of adductor nerve axons to the PCA muscle. A varying degree of regeneration of injured recurrent laryngeal nerves (RLN) in humans of more than 6 months confirms subclinical reinnervation, which may prevent denervation-induced atrophy. Summary Several promising surgical techniques have been developed for bilateral selective reinnervation for BVFP patients. This involves reinnervation of the abductor and adductor laryngeal muscles. The surgical technique aims at reinnervating the PCA muscle to trigger abduction during the respiratory cycle and preservation of good voice by strengthening the adductor muscles as well as prevention of laryngeal synkinesis. © 2011 Lippincott Williams & Wilkins, Inc.