Nose and paranasal sinuses: Edited by Anshul SamaOutcomes following surgical decompression for dysthyroid orbitopathy (Graves' disease)Leong, Samuel Ca; White, Paul SbAuthor Information aDepartment of Paediatric Otolaryngology – Head and Neck Surgery, Alder Hey Children's NHS Foundation Trust, Liverpool, England bDepartment of Otolaryngology – Head and Neck Surgery, Ninewells Hospital and Medical School, Dundee, Scotland, UK Correspondence to Mr. Paul S. White, FRACS, FRCS, Department of Otolaryngology – Head and Neck Surgery, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland, UK Tel: +44 1382 660111 ext. 36113; fax: +44 1382 632816; e-mail: [email protected] Current Opinion in Otolaryngology & Head and Neck Surgery: February 2010 - Volume 18 - Issue 1 - p 37-43 doi: 10.1097/MOO.0b013e328335017c Buy Metrics Abstract Purpose of review Graves' disease is a multiorgan autoimmune disease of complex pathophysiology that primarily affects the thyroid gland and orbit. The ophthalmic manifestations of Graves' disease may vary from mild proptosis which causes minimal cosmetic embarrassment to subluxation of the globe, exposure keratitis, corneal abrasion and even blindness. This article focuses on outcomes following orbital decompression. Recent findings Surgical techniques have evolved with improved understanding of sinonasal anatomy and being technology-driven with the use of the fiberoptic endoscope and image guidance. The most common surgical outcome reported in the literature is reduction in proptosis, followed by visual acuity and intraocular pressure. Quality-of-life assessments are not routinely measured. Summary There are a myriad of surgical techniques currently in practice which underscores the fact that no single technique is clearly superior to another. Endoscopic decompression results in a mean reduction of 3.50 mm and is associated with a low complication rate. Nevertheless, the literature suggests that the best techniques are likely to be multiwall approaches such as combined medial and lateral wall decompression. Management of dysthyroid ophthalmopathy is clearly multidisciplinary. Future studies should consider a minimum data set for reporting outcome measures which should include a quality of life tool. © 2010 Lippincott Williams & Wilkins, Inc.