Nose and paranasal sinusesEvaluation of spontaneous nasal cerebrospinal fluid leaksWise, Sarah K; Schlosser, Rodney JAuthor Information Department of Otolaryngology–Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA Correspondence to Rodney J. Schlosser, MD, Department of Otolaryngology–Head and Neck Surgery, 135 Rutledge Ave, Suite 1130, PO Box 250550, Medical University of South Carolina, Charleston, SC 29425, USA Tel: +1 843 792 7165; fax: +1 843 792 0546; e-mail: [email protected] Current Opinion in Otolaryngology & Head and Neck Surgery: February 2007 - Volume 15 - Issue 1 - p 28-34 doi: 10.1097/MOO.0b013e328011bc76 Buy Metrics Abstract Purpose of review Spontaneous nasal cerebrospinal fluid (CSF) leaks represent a distinct clinical entity that presents important diagnostic and therapeutic challenges. Recognition of the proper demographic group and presenting symptoms, as well as the radiologic features of this disease process, are integral to making the appropriate diagnosis. In addition, this patient group requires special perioperative and intraoperative considerations for suitable management. Recent findings Current literature echoes previously published success rates for endoscopic repair of CSF leaks at or above 90%. Success rates for closure of spontaneous CSF leaks, however, continue to be the lowest in comparison with other CSF leak etiologies. The increased failure rate for spontaneous CSF leak repair is likely due to the increased intracranial pressure present in this patient group. Patients with spontaneous CSF leaks are increasingly being recognized as belonging to a group inclusive of patients with benign intracranial hypertension and empty sella syndrome. Summary In this review, we highlight the demographic characteristics, clinical presentation and radiologic findings that distinguish spontaneous nasal CSF leak patients from those with other CSF leak etiologies. We also discuss perioperative measures advocated for patients with spontaneous nasal CSF leaks that may aid in the success of their surgical repair. © 2007 Lippincott Williams & Wilkins, Inc.