Cataract surgery and lens implantationIs cataract surgery a risk factor for progression of macular degeneration?Patel, Jignesh I Author Information Ophthalmology Department, Royal Perth Hospital, Perth, Australia Correspondence to Jignesh I. Patel, Ophthalmology Department, Royal Perth Hospital, Wellington St, Perth, Western Australia 6008, Australia Tel: +61 8 9224 2298; fax: +61 8 9224 1391; e-mail: [email protected] Current Opinion in Ophthalmology: February 2007 - Volume 18 - Issue 1 - p 9-12 doi: 10.1097/ICU.0b013e3280112a0f Buy Metrics Abstract Purpose of review There is a suggestion of increased risk or progression of age-related macular degeneration after cataract surgery, which is related to the increased exposure of the retina to short-wavelength light. Recent findings Cell culture and animal work has described retinal and retinal pigment epithelium phototoxicity on acute light exposure. Clinical studies suggest that the use of short-wavelength-blocking intraocular lenses can help but may also affect visual function and circadian rhythm. Summary Evidence to date fails to prove conclusively that light alone or cataract surgery can induce or cause the progression of age-related macular degeneration. A randomized clinical study of the use of short-wavelength (blue)-blocking lenses to prove or disprove the ability of these intraocular lenses to help in preventing progression of age-related macular degeneration is needed. © 2007 Lippincott Williams & Wilkins, Inc.