CATARACT SURGERY AND LENS IMPLANTATION: Edited by Natalie A. AfshariEndophthalmitis after cataract surgery: an update on recent advancesPeck, Travis J.; Patel, Samir N.; Ho, Allen C. Author Information Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, PA Correspondence to Allen C. Ho, MD, Ophthalmology, Mid Atlantic Retina, The Retina Service of Wills Eye Hospital, Thomas Jefferson University, 840 Walnut Street, Suite 1020, Philadelphia, PA 19107, USA. E-mail: [email protected] Current Opinion in Ophthalmology: January 2021 - Volume 32 - Issue 1 - p 62-68 doi: 10.1097/ICU.0000000000000727 Buy Metrics Abstract Purpose of review Prevention and management of postcataract endophthalmitis remain quite relevant for anterior segment and vitreoretinal surgeons. Although the Endophthalmitis Vitrectomy Study, published in 1996, remains the only level 1 evidence for the management of postcataract endophthalmitis, recent advances have resulted in an evolution of practice patterns. The aim of this review is to summarize the literature regarding postcataract endophthalmitis with a focus on the last 18 months. Recent findings The IRIS registry indicates the rates of endophthalmitis are decreasing in the United States, and the outcomes appear to be improving. Intracameral moxifloxacin has become more widely accepted and intracameral vancomycin has been shown to be associated with retinal vasculitis. The role of systemic antibiotics and vitrectomy is unclear and practice patterns vary widely. Summary Although practice patterns vary, prevention and treatment of endophthalmitis after cataract surgery continues to improve. More uniform guidelines regarding surgical and medical therapy are necessary but the standard of prompt referral to a vitreoretinal specialist for immediate intravitreal antibiotics remains the most important intervention in the management of postcataract endophthalmitis. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.