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Optical coherence tomography angiography in glaucoma

Bojikian, Karine D.; Chen, Philip P.; Wen, Joanne C.

Current Opinion in Ophthalmology: March 2019 - Volume 30 - Issue 2 - p 110–116
doi: 10.1097/ICU.0000000000000554
GLAUCOMA: Edited by Donald L. Budenz

Purpose of review Optical coherence tomography angiography (OCTA) studies have demonstrated reduced microcirculation in the superficial optic nerve, peripapillary retina, and the macula of glaucoma patients. The scope of this review is to outline recent studies using OCTA in glaucoma and highlight how OCTA may help improve diagnosis and follow-up in glaucoma patients.

Recent findings OCTA studies have provided evidence of vascular changes in the optic nerve head, peripapillary, and macula region in glaucoma in comparison to glaucoma suspects and normal eyes. Additionally, OCTA can detect longitudinal reduction of peripapillary and macula vessel density in glaucoma patients. It remains unclear whether the reduced microcirculation in glaucoma patients induces the neuronal damage or arises through reduced circulation requirements in damaged tissue.

Summary OCTA is a novel imaging modality that has great potential to enhance our understanding of glaucoma and to improve our ability to detect and treat it.

Department of Ophthalmology, University of Washington, Seattle, Washington, USA

Correspondence to Joanne C. Wen, MD, Department of Ophthalmology, University of Washington, Box 359608, 325 Ninth Avenue, Seattle, WA 98104, USA. Tel: +1 206 744 2020; fax: +1 206 685 7055; e-mail:

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