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Current opinion in ophthalmology

novel glaucoma devices in the pipeline

Ittoop, Sabita M.a; Seibold, Leonard K.b; Kahook, Malik Y.b

Current Opinion in Ophthalmology: March 2019 - Volume 30 - Issue 2 - p 117–124
doi: 10.1097/ICU.0000000000000555
GLAUCOMA: Edited by Donald L. Budenz

Purpose of review Adherence to chronic use of topical intraocular pressure (IOP) lowering medications is a fundamental barrier to successful, long-term control in patients suffering from glaucoma. This has fueled innovation to create new vehicles for drug administration, new drug formulations with enhanced bioavailability, and minimally invasive glaucoma surgeries (MIGS) with improved risk–benefit profiles to enhance sustained IOP control. The present article is an overview of novel devices in the pipeline.

Recent findings Several new devices that promise to deliver sustained drug therapy and reduce dependence on daily patient adherence are currently being vetted through clinical trials. In addition, the pipeline for new MIGS devices that target sustained IOP control continues to grow.

Summary Alternative drug delivery approaches and novel MIGS devices broaden the treatment options for patients with glaucoma. This will allow the clinician to customize treatment by selecting specific approaches based on each patient's individual needs and coexisting ocular pathologies. Additional comprehensive, large-scale, clinical studies will help define the role that these options hold in a constantly evolving treatment paradigm.

aGlaucoma Consultants of Washington Inc., Herndon, Virginia

bUniversity of Colorado School of Medicine, Aurora, Colorado, USA

Correspondence to Malik Y. Kahook, MD, University of Colorado School of Medicine, 1675 Aurora Ct, Aurora, CO 80045, USA. Tel: +1 720 848 2501; fax: +1 720 848 5014; e-mail:

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