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Emerging trends in contact lens-related infections

Cheung, Natalie; Nagra, Parveen; Hammersmith, Kristin

Current Opinion in Ophthalmology: July 2016 - Volume 27 - Issue 4 - p 327–332
doi: 10.1097/ICU.0000000000000280

Purpose of review This article reviews the literature on past and recent trends in contact lens-related microbial keratitis from bacterial, fungal, and Acanthamoeba infections.

Recent findings Contact lens wear is the most important risk factor for microbial keratitis. Despite increased use of daily disposable contact lens wear, the incidence of bacterial ulcers related to contact lens wear remains high. Overnight contact lens wear is the leading risk factor in contact lens-related bacterial infections. There may be a trend towards increasing antibiotic resistance of Gram-positive bacteria to fourth-generation fluoroquinolones. The incidence of Acanthamoeba and fungal infections, despite resolution of two outbreaks involving multipurpose solutions, are also on the rise.

Summary Contact lens-related microbial keratitis is rising and may be associated with more severe, vision threatening, infections.

Wills Eye Hospital, Philadelphia, Pennsylvania, USA

Correspondence to Kristin Hammersmith, 840 Walnut Street, Suite 920, Philadelphia, PA 19107, USA. Tel: +1 215 928 3854; e-mail:

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