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Clinical utility of intraoperative optical coherence tomography

Khan, Mehnaz; Ehlers, Justis P.

Current Opinion in Ophthalmology: May 2016 - Volume 27 - Issue 3 - p 201–209
doi: 10.1097/ICU.0000000000000258
RETINAL, VITREOUS AND MACULAR DISORDERS: Edited by Brandon G. Busbee and John W. Kitchens

Purpose of review To explore the clinical utility of intraoperative optical coherence tomography (iOCT) for the management of vitreoretinal conditions.

Recent findings The role of iOCT in guiding surgical decision-making and surgical manipulations during vitreoretinal procedures has been evaluated by multiple studies. This imaging modality is emerging as a valuable asset during procedures for vitreoretinal interface disorders, retinal detachments, submacular surgeries and therapeutics, and in pediatric conditions such as retinopathy of prematurity. iOCT allows the surgeon to assess completion of surgical goals and to directly monitor the architectural impact of instrument–tissue interactions that may correlate with eventual prognosis. The technology has gone through numerous iterations with the eventual goal being the development of a user-friendly, efficient, and integrated system that provides surgeons with ‘real-time’ feedback during ophthalmic surgeries to allow for a comprehensive image-assisted vitreoretinal surgery platform.

Summary The role of iOCT in ophthalmic surgery has been evolving with the help of ongoing research to define its utility in the operating room and to develop integrative technologies. Advancements in OCT-friendly surgical instrumentation and in integrative capabilities of this technology may help achieve more widespread adoption of this technology in the vitreoretinal surgical theater. Although the evidence appears clear that this technology impacts surgical decision-making, additional research is needed. However, further research is needed to determine the influence of this technology on overall patient outcomes.

Ophthalmic Imaging Center, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USA

Correspondence to Justis P. Ehlers, MD, Cole Eye Institute, Cleveland Clinic Foundation, 9500 Euclid Ave/i32, Cleveland, OH 44195, USA. E-mail:

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