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Cataract surgery in pseudoexfoliation syndrome

Belovay, Graham Wa; Varma, Devesh Ka; Ahmed, Iqbal Ike Ka,b

Current Opinion in Ophthalmology: January 2010 - Volume 21 - Issue 1 - p 25–34
doi: 10.1097/ICU.0b013e328332f814
Cataract surgery and lens implantation: Edited by Natalie Afshari

Purpose of review To discuss the preoperative, intraoperative and postoperative considerations and techniques for cataract surgery in pseudoexfoliation syndrome.

Recent findings Pseudoexfoliation syndrome is a common disorder worldwide that has been linked to the lysyl oxidase-like-one (LOXL1) gene. Its identification in patients undergoing cataract surgery has become important in preventing complications through proper preoperative planning. The management of the small pupil found in pseudoexfoliation can be achieved using various pharmacological and mechanical techniques. There are now several devices available to support the weak zonules that commonly accompany pseudoexfoliation. Postoperatively, pseudoexfoliation patients need to be followed closely to monitor for complications such as intraocular pressure spikes, inflammation and intraocular lens dislocation.

Summary With proper preoperative preparation, intraoperative use of appropriate adjunctive devices, and close postoperative follow-up, favorable outcomes can be achieved in cataract surgery in pseudoexfoliation syndrome.

aUniversity of Toronto, Toronto, Ontario, Canada

bUniversity of Utah, Salt Lake City, Utah, USA

Correspondence to Iqbal Ike K. Ahmed, MD, Credit Valley EyeCare, 3200 Erin Mills Parkway, Unit 1, Mississauga, ON L5L 1W8, Canada Tel: +1 905 820 3937; fax: +1 905 820 0111; e-mail:

© 2010 Lippincott Williams & Wilkins, Inc.