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Ocular disease in pregnancy

Schultz, Kara L; Birnbaum, Andrea D; Goldstein, Debra A

Current Opinion in Ophthalmology: October 2005 - Volume 16 - Issue 5 - p 308-314
doi: 10.1097/
Ocular manifestations of systemic disease part I

Purpose of review Pregnancy may cause ocular changes, both physiologic and pathologic, and may be associated with the development of new disease or may alter the course of preexisting disease. This paper discusses these changes and reviews diabetic retinopathy, uveitis, preeclampsia, cortical blindness and central serous chorioretinopathy.

Recent findings Recent reports have contributed to our understanding of the pathophysiology of diabetic retinopathy and cortical blindness associated with preeclampsia, the impact of pregnancy on the course of inflammatory eye disease, and the use of optical coherence tomography in following central serous chorioretinopathy in pregnant women.

Summary This improved understanding of the pathophysiology of ocular disease in pregnancy and the impact of pregnancy on the course of preexisting ocular disease offers the opportunity for meaningful counseling of women who are pregnant or planning to become pregnant.

Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Illinois, USA

The authors have no commercial or proprietary interest in the material presented in this paper.

Correspondence to Debra A Goldstein, MD, 1855 West Taylor Street, MC 648, Chicago, IL 60612, USA

Tel: 312 996 6660; fax: 312 996 2913; e-mail:

© 2005 Lippincott Williams & Wilkins, Inc.