How to prevent human papillomavirus-related oropharyngeal cancer? : Current Opinion in Oncology

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HEAD AND NECK: Edited by Joel Guigay

How to prevent human papillomavirus-related oropharyngeal cancer?

Ferrando-Díez, Angelicaa; Pavón, Miguel Angelb,c; Cirauqui, Beatriza; Alemany, Laiab,c; Mesía, Ricarda

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Current Opinion in Oncology 35(3):p 145-150, May 2023. | DOI: 10.1097/CCO.0000000000000937


Purpose of review 

Human papillomavirus (HPV) is responsible of the increasing incidence rates of oropharyngeal squamous cell carcinoma (OPSCC) in high-income countries. This significant epidemiological change requires several and diverse prevention strategies.

Recent findings 

The cervical cancer prevention model is the paradigm of HPV-related cancer, and its success provides encouragement for the development of similar methods to prevent HPV-related OPSCC. However, there are some limitations that hinder its application in this disease. Here, we review the primary, secondary and tertiary prevention of HPV-related OPSCC and discuss some directions for future research.


The development of new and targeted strategies to prevent HPV-related OPSCC is needed since they could definitely have a direct impact on the reduction of morbidity and mortality of this disease.

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