FERTILITY, IVF AND REPRODUCTIVE GENETICS: Edited by Emre Seli and Juan A. Garcia VelascoAssisted reproductive technology for women with endometriosis, a clinically oriented reviewAta, Barisa; Telek, Savci Bekirb Author Information aDepartment of Obstetrics and Gynecology, Koç University School of Medicine bDepartment of Obstetrics and Gynecology, Istanbul University Istanbul School of Medicine, Istanbul, Turkish Republic Correspondence to Baris Ata, Professor and Chairperson, Department of Obstetrics and Gynecology, Koç University Hospital, Davutpasa Cad. No:4, Zeytinburnu, Istanbul 34010 Turkish Republic. E-mail: [email protected] Current Opinion in Obstetrics and Gynecology: June 2021 - Volume 33 - Issue 3 - p 225-231 doi: 10.1097/GCO.0000000000000710 Buy Metrics Abstract Purpose of review To discuss optimal management of an assisted reproductive technology (ART) cycle in women with endometriosis. Recent findings New studies involving euploid embryo transfers provide more insight on the etiology of endometriosis-associated infertility. Oocyte competence to reach live birth seems unlikely to be affected by the disease. Routine medical or surgical treatment prior to an ART cycle does not appear beneficial. Short gonadotropin releasing hormone (GnRH) antagonist or progestin primed ovarian stimulation protocols seem to be proper first choices, depending on the intention for a fresh embryo transfer. Low-quality evidence supports frozen thawed over fresh embryo transfer. Ovarian stimulation for ART does not seem to be associated with symptom progression or recurrence. Summary How endometriosis affects fertility is still unclear, but ART is an effective pragmatic treatment. Each woman with endometriosis must be assessed with a holistic approach, and in the absence of an indication for otherwise, ART cycles can be kept simple with patient-friendly protocols. Whether a frozen embryo transfer is better than a fresh one should be investigated. Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.