FAMILY PLANNING: Edited by Paul D. BlumenthalAdvances in the management of early pregnancy lossHenkel, Andrea; Shaw, Kate A.Author Information Division of Family Planning Services & Research, Department of Obstetrics & Gynecology, Stanford University, Stanford, California, USA Correspondence to Andrea Henkel, MD, 300 Pasteur Drive, Room HG332, Stanford, CA 94305, USA. Tel: +1 651 402 4324; e-mail: [email protected] Current Opinion in Obstetrics and Gynecology: December 2018 - Volume 30 - Issue 6 - p 419-424 doi: 10.1097/GCO.0000000000000501 Buy Metrics Abstract Purpose of review To describe recent advances in management of early pregnancy loss. Recent findings Addition of mifepristone to current protocols for medical management of miscarriage increases effectiveness of a single dose of misoprostol and significantly reduces subsequent aspiration procedures. Women with an incomplete evacuation after medical management may be treated expectantly with similar rates of complete expulsion compared with surgical management at 6 weeks. As cytogenetic analysis improves, analysis of products of conception can be performed whether collected after surgical or medical management and is an efficient strategy in starting a recurrent pregnancy loss work-up. For those seeking pregnancy after miscarriage, conception immediately following an early pregnancy loss is not associated with increased risk of subsequent miscarriage. However, recent studies suggest that the original intendedness of the pregnancy resulting in miscarriage does not predict future reproductive goals of the woman, so family planning should be discussed at the time of miscarriage. Summary Miscarriage is a common experience among reproductive-aged women and advances in medical management and modern-day aspiration techniques make the use of the sharp curette obsolete. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.