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Scratching and IVF: any role?

Ko, Jennifer Ka Yee; Ng, Ernest Hung Yu

Current Opinion in Obstetrics and Gynecology: June 2016 - Volume 28 - Issue 3 - p 178–183
doi: 10.1097/GCO.0000000000000264
FERTILITY, IVF AND REPRODUCTIVE GENETICS: Edited by Emre Seli and Juan Antonio García Velasco

Purpose of review To review updated information on the influence of endometrial scratching on IVF.

Recent findings Endometrial receptivity remains an important rate-limiting step affecting the success of IVF. The current evidence on the effect of endometrial scratching on IVF ranges from marked improvement, no difference to a potentially negative impact. The heterogeneity of studies presents a challenge in interpretation of data for routine clinical practice.

Summary Endometrial scratching performed in the preceding cycle is associated with improved clinical pregnancy and live birth rates in women with recurrent implantation failure, but not in unselected subfertile women undergoing IVF. Most of the current literature are underpowered and at high risk of bias.

Department of Obstetrics and Gynaecology, The University of Hong Kong, Hong Kong

Correspondence to Jennifer K.Y. Ko, University of Hong Kong, Hong Kong, Hong Kong. Tel: +852 22554647; fax: +852 28550947; e-mail:

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