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Hormone replacement therapy post Women's Health Initiative study: where do we stand?

Calleja-Agius, Jean; Brincat, Mark P

Current Opinion in Obstetrics and Gynecology: December 2008 - Volume 20 - Issue 6 - p 513–518
doi: 10.1097/GCO.0b013e32830dfa5c
Women's health: Edited by Gubby Ayida and Joseph Aquilina

Purpose of review The aim of this review is to look at all publications from the past 18 months, which deal with the impact of the Women's Health Initiative Trial on hormone replacement therapy.

Recent findings There is a definite decline in the use of hormone replacement therapy among menopausal women.

Summary More research needs to be done on the long-term effects of hormone replacement therapy, especially with regard to ultra-low dose hormone therapy.

Department of Obstetrics and Gynaecology, Mater Dei Hospital, Msida, Malta

Correspondence to Dr Jean Calleja-Agius MD, MRCOG, MRCPI, Academic Senior Registrar (Obstetrics and Gynaecology), 12, ‘Mon Nid’, G. Faure Street, Tarxien TXN 2421, Malta Tel: +356 21693041; fax: +356 23331027; e-mail:

© 2008 Lippincott Williams & Wilkins, Inc.