Gynecologic oncology and pathologyVaginal cancersCreasman, William TAuthor Information Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston, South Carolina, USA Correspondence to William T. Creasman, MD, Department of Obstetrics and Gynecology, Medical University of South Carolina, 96 Jonathan Lucas Street, Box 250619, Suite 634CSB, Charleston, SC 29425, USA Tel: +1 843 792 4509; fax: +1 843 792 0533; e-mail: [email protected] Current Opinion in Obstetrics and Gynecology: February 2005 - Volume 17 - Issue 1 - p 71-76 Buy SDC Abstract Purpose of review Vaginal neoplasia is one of the rarest of malignancies. Intraepithelial lesions are usually first identified by an abnormal Pap smear in a woman without a cervix. Surgery or ablation of the epithelium is usually highly successful. Recent findings There have not been any findings of significance since 2003 to include in this review. Summary Invasive cancer is usually located in the upper one-third of the vagina. If staged early, radical surgery can be curative as well as radiation therapy. Like cervical cancer, a more advanced stage is treated with radiation therapy, but with poorer survival rates than cervical cancer. Abbreviation VAIN: vaginal intraepithelial neoplasia. Copyright © 2005 YEAR Wolters Kluwer Health, Inc. All rights reserved.