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Direct vascular effects of estrogens and selective estrogen receptor modulators

Simoncini, Tommasoa,b; Genazzani, Andrea Ra

Current Opinion in Obstetrics and Gynecology: June 2000 - Volume 12 - Issue 3 - p 181-187
Review Article
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The aim of this review is to provide an update on the latest advancements in the field of the action of estrogens on the cardiovascular system, and particularly on the molecular mechanisms of the direct effects of these hormones and of some of the new synthetic selective estrogen receptor modulators on the vascular wall.

aDepartment of Reproductive Medicine and Child Development, Division of Obstetrics and Gynecology, University of Pisa, Pisa, Italy; and bScuola Superiore di Studi e di Perfezionamento ‘S. Anna’, Pisa, Italy

Correspondence to Professor Andrea R. Genazzani, Department of Reproductive Medicine and Child Development, Division of Obstetrics and Gynecology, University of Pisa, Via Roma, 67, 56100 Pisa, Italy.. Tel: +39 050 553412; fax: +39 050 553410; e-mail: a.genazzani@obgyn.med.unipi.it

© 2000 Lippincott Williams & Wilkins, Inc.