HEADACHE: Edited by Peter J. GoadsbyMultisensory integration in migraineSchwedt, Todd J.Author Information Department of Neurology, Mayo Clinic, Phoenix, Arizona, USA Correspondence to Todd J. Schwedt, MD, MSCI, Associate Professor of Neurology, Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ 85054, USA. Tel: +1 480 342 3078; fax: +1 480 342 3083; e-mail: email@example.com Current Opinion in Neurology: June 2013 - Volume 26 - Issue 3 - p 248-253 doi: 10.1097/WCO.0b013e328360edb1 Buy Metrics Abstract Purpose of review Migraine attacks consist of head pain and hypersensitivities to somatosensory, visual, auditory, and olfactory stimuli. Investigating how the migraine brain simultaneously processes and responds to multiple incoming stimuli may yield insights into migraine pathophysiology and migraine symptoms. Recent findings The presence and intensity of hypersensitivity to one stimulus type are positively associated with the presence and intensity of hypersensitivities to other stimuli and to headache intensity. Furthermore, exposure to visual, auditory, and olfactory stimuli can trigger migraine attacks. These relationships suggest a role for multisensory integration in migraine. Summary Multisensory integration of somatosensory, visual, auditory, and olfactory stimuli by the migraine brain may be an important concept for understanding migraine. © 2013 Lippincott Williams & Wilkins, Inc.