Cerebrovascular disease: Edited by Patrik MichelIntracerebral hemorrhage: getting ready for effective treatmentsRincon, Freda; Mayer, Stephan AbAuthor Information aDepartment of Medicine, Division of Neurology and Critical Care, Cooper University Hospital, University of Medicine and Dentistry of New Jersey, Camden, New Jersey, USA bDepartment of Neurology and the Department of Neurosurgery, Division of Stroke and Critical Care, Neurological Intensive Care Unit, College of Physicians and Surgeons, Columbia University, New York, New York, USA Correspondence to Stephan A. Mayer, MD, FCCM, Neurological Intensive Care Unit, Neurological Institute, 710 West 168th Street, Unit 39, New York, NY 10032, USA Tel: +1 212 305 7236; fax: +1 212 305 2792; e-mail: [email protected] Current Opinion in Neurology: February 2010 - Volume 23 - Issue 1 - p 59-64 doi: 10.1097/WCO.0b013e3283352c01 Buy Metrics Abstract Purpose of review Spontaneous intracerebral hemorrhage (ICH) is the most devastating type of stroke and a leading cause of disability and mortality in the United States and the rest of the world. The purpose of this article is to review recent advances in the management of spontaneous intracerebral hemorrhage. Recent findings Although no interventions have consistently shown an improvement of mortality or functional outcomes after ICH, results from multicenter prospective randomized controlled trials have shown that early hemostasis to prevent hematoma growth, removal of clot by surgical or minimally invasive interventions, clearance of intraventricular hemorrhage, and adequate blood pressure control for the optimization of cerebral perfusion pressure may constitute the most important therapeutic goals to ameliorate secondary neurological damage, decrease mortality, and improve functional outcomes after ICH. Conclusion Several promising methods may be ready for routine clinical use in a few years to decrease disability and mortality from ICH. © 2010 Lippincott Williams & Wilkins, Inc.