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Acute vestibulopathy

Strupp, Michael; Arbusow, Viktor

Current Opinion in Neurology: February 2001 - Volume 14 - Issue 1 - p 11-20
Review Article

Acute vestibulopathy is characterized by the acute or subacute onset of vertigo, dizziness or imbalance with or without ocular motor, sensory, postural or autonomic symptoms and signs, and can last for seconds to up to several days. Acute vestibular lesions may result from a hypofunction or from pathological excitation of various peripheral or central vestibular structures (labyrinth, vestibular nerve, vestibular nuclei, cerebellum or ascending pathways to the thalamus and the cortex). This update focuses on new aspects of the aetiology, pathophysiology, epidemiology, and treatment of (i) acute peripheral disorders (benign paroxysmal positioning vertigo, vestibular neuritis, Menière's disease, perilymph fistula, especially ‘superior canal dehiscence syndrome’, vestibular paroxysmia); and (ii) acute central vestibular disorders (especially ‘vestibular migraine’). Finally, the clinical relevance of recent diagnostic tools (three-dimensional analysis of eye movement, imaging techniques) is discussed.

Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians University, Munich, Germany

Correspondence to Michael Strupp, MD, Department of Neurology, University of Munich, Klinikum Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany. Tel: +49 89 7095 2585; fax: +49 89 7095 5584 or 8883; e-mail:

© 2001 Lippincott Williams & Wilkins, Inc.