Cerebrovascular DiseaseIon channels and exchangers that mediate ischemic neuronal injuryVornov, James J.Author Information Cerebrovascular Program, Cellular and Molecular Medicine Program, Departments of Neurology and Neuroscience, Johns Hopkins Hospital, Meyer 5‐185, 600 North Wolfe St, Baltimore, MD 21287‐6953, USA Abbreviations; TTX: tetrodotoxin; VSCC: voltage sensitive calcium channel; Current Opinion in Neurology: February 1998 - Volume 11 - Issue 1 - p 39-43 Buy Abstract Preventing the loss of ion homeostasis or promoting its recovery are two primary targets of neuroprotective strategies. The contribution of excitatory neurotransmitter receptor linked ion channels is now well established. Sodium and calcium may also enter neurons and glia through voltage sensitive channels and exchangers, contributing directly and indirectly to injury. Curr Opin Neurol 11:39–43. © 1998 Rapid Science Ltd © Lippincott-Raven Publishers.