Current Opinion in Nephrology and Hypertension was launched in 1992. It is part of a successful series of review journals whose unique format is designed to provide a systematic and critical assessment of the literature as presented in the many primary journals. The field of nephrology and hypertension is divided into 12 sections that are each reviewed once a year. Each section is assigned a Section Editor, a leading authority in the area, who identifies the most important topics at that time. Here we are pleased to introduce the Section Editors for this issue.
Myles Wolf is the Margaret Gray Morton Professor of Medicine at the Feinberg School of Medicine at Northwestern University in Chicago, Illinois, USA. He is the founding Director of the Center for Translational Metabolism and Health within the Institute for Public Health and Medicine at the Feinberg School.
Dr Wolf received his medical degree from the State University School of New York Downstate in Brooklyn, New York, USA. He completed internal medicine training at the Massachusetts General Hospital and a nephrology fellowship at the Massachusetts General Hospital and the Brigham and Women's Hospital in Boston, Massachusetts, USA. During his research fellowship training, Dr Wolf obtained a Masters of Medical Sciences in clinical and physiological investigation from Harvard Medical School, also in Boston. After serving on the faculty of Harvard Medical School for five years, Dr Wolf moved to the University of Miami, Miller School of Medicine, USA, where he eventually served as Chief of the Division of Nephrology and Hypertension, Director of the University of Miami Clinical Research Center, and Assistant Dean for Translational and Clinical Research.
The focus of Dr Wolf's research is disordered mineral metabolism across the spectrum of chronic kidney disease, including dialysis, kidney transplantation and earlier stages. His research has been published in leading general medicine and subspecialty journals including the New England Journal of Medicine, JAMA, the Journal of Clinical Investigation, Circulation, Journal of the American Society of Nephrology, and Kidney International, among others. His primary contributions have been in the area of hormonal regulation of phosphate and vitamin D homeostasis. He has helped to characterize the physiological role of fibroblast growth factor 23 (FGF23) in health and in chronic kidney disease, and the impact of elevated FGF23 levels on adverse clinical outcomes in patients with kidney disease.
During the past decade, Dr Wolf's research on mineral metabolism has been supported by grants from the American Heart Association, the National Kidney Foundation, the American Society of Nephrology, and the National Institutes of Health. He has served as primary research mentor for students, residents, fellows and faculty members involved in patient-oriented, epidemiological and basic laboratory research. He serves on the editorial boards for Journal of the American Society of Nephrology, Clinical Journal of the American Society of Nephrology, and Seminars in Nephrology, and as an ad hoc peer reviewer for several other journals. Dr Wolf has been invited to deliver numerous national and international lectures on his research, and has been the recipient of teaching and mentoring awards. In 2010, he was elected to the American Society of Clinical Investigation.
David A. Bushinsky
David A. Bushinsky, is the John J. Kuiper Distinguished Professor of Medicine and of Pharmacology and Physiology at the University of Rochester School of Medicine, USA. He is Chief of the Nephrology Division at the University of Rochester Medical Center and Associate Chair for Academic Affairs in the Department of Medicine.
Dr Bushinsky has published several hundred peer-reviewed articles, invited reviews, chapters and editorials focusing on disorders of divalent ion metabolism. He has developed a strain of rats that exhibit genetic hypercalciuria, the most common metabolic abnormality in humans with nephrolithiasis, and spontaneously form kidney stones. The pathophysiology of the hypercalciuria closely parallels that of man and is thus a useful model to study stone formation in humans. He has also extensively studied the mechanism by which metabolic acids induce physicochemical bone dissolution and cell-mediated bone resorption. His research has been consistently funded by grants from the National Institutes of Health for 3 decades. Dr Bushinsky has lectured throughout the world on stone formation, effects of acid on bone and other disorders of divalent ion metabolism.
Dr Bushinsky received his medical degree from Tufts University School of Medicine in Boston, Mass., USA. He completed an internship and residency at Tufts New England Medical Center Hospital in Boston, Mass., USA. He also completed a fellowship in clinical nephrology and a research fellowship in nephrology at Tufts New England Medical Center Hospital in Boston, Mass.
Dr Bushinsky is a member of a number of organizations including the Association of American Physicians and the American Society for Clinical Investigation.
Orson W. Moe
Orson W. Moe received his medical degree from the University of Toronto, Canada and is currently Professor of Internal Medicine and Physiology at the University of Texas Southwestern Medical Center, Dallas, TX, USA. He is the Director of the Charles and Jane Pak Center of Mineral Metabolism and Clinical Research. He is also an active clinician and researcher in the Nephrology Division at Southwestern. Moe is the holder of the Charles and Jane Pak Distinguished Chair in Mineral Metabolism Research and the Donald Seldin Professorship in Clinical Investigation.
Dr Moe conducts both basic science and patient-oriented research on renal physiology and metabolism, and epithelial biology. His research strives to cross from the level of the whole patient, to animal and cell culture models, and down to single molecules. He is active in teaching at the undergraduate and post-graduate level nationally and internationally.
In addition to editing Current Opinion in Nephrology and Hypertension, Dr Moe also serves on the editorial board of the American Journal of Physiology and edits the textbook, The Kidney by Seldin and Giebisch. Dr Moe is currently a member of the American Society of Clinical Research, American Association of Physicians, American Society of Nephrology, and American Physiologic Society.
Susan Quaggin graduated from the Faculty of Medicine at the University of Toronto, Canada, in 1988 and received her specialty degree in internal medicine in 1992. She completed her sub-specialty training in nephrology in 1993 at University of Toronto and did a post-doctoral fellowship at Yale University, USA, where she studied the genetic basis of kidney development. Dr Quaggin has served as an elected councillor of the American Society for Clinical Investigation (ASCI), is a member of the Executive Council of the ISN and was elected to the American Association of Physicians (AAP) in 2013. In addition, Dr Quaggin sits on the editorial boards of several journals, is the Deputy Editor of the Journal of the American Society of Nephrology and has organized a number of international renal and vascular meetings.
In January 2013, Dr Quaggin joined Northwestern University Feinberg School of Medicine, USA, as the Charles Horace Mayo Professor of Medicine, where she serves as the Director of the Feinberg Cardiovascular Research Institute (FCVRI) and Chief of the Division of Nephrology.
Dr Quaggin's research program focuses on genetic pathways required to establish and maintain the integrity of microvascular beds including the glomerular filtration barrier – a highly selective filter that separates the blood from the urinary space. To understand the pathways and interactions between perivascular cells and the endothelium, her research team has developed a number of genetic models that permit cell and time-specific manipulation of gene expression.