EPIDEMIOLOGY AND PREVENTION: Edited by Navdeep TangriBlood pressure targets in chronic kidney disease an update on the evidenceGuerrot, Dominiquea , b; Humalda, Jelmer K.cAuthor Information aNormandie University, UNIROUEN, INSERM U1096, FHU REMOD-VHF bNephrology Department, Rouen University Hospital, Rouen, France cDepartment of Nephrology, Radboud University Medical Center, Nijmegen, The Netherlands Correspondence to Dominique Guerrot, Nephrology Department, Rouen University Hospital, 76031 Rouen, France. Tel: +33 2 32 88 90 02; fax: +33 232889115; e-mail: email@example.com Current Opinion in Nephrology and Hypertension: May 2020 - Volume 29 - Issue 3 - p 327-332 doi: 10.1097/MNH.0000000000000601 Buy Metrics Abstract Purpose of review Hypertension is the leading modifiable cause of cardiovascular events and of mortality and is generally considered as a direct cause of chronic kidney disease. Defining optimal blood pressure targets in patients with chronic kidney disease is therefore of critical importance. Recent findings Over the recent years, results and post-hoc analyses of several important trials comparing blood pressure targets which included patients with chronic kidney disease have been published. Although these results provide important means to understand the consequences of high blood pressure and to improve the management of hypertension in chronic kidney disease, they led to remarkably different interpretations and recommendations in the current guidelines. Summary The present review summarizes the current evidence and areas of controversy for the definition of blood pressure targets in patients with chronic kidney disease. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.