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Moderate alcohol consumption: effects on lipids and cardiovascular disease risk

van Tol, Ariea; Hendriks, Henk F.J.b

Current Opinion in Lipidology: February 2001 - Volume 12 - Issue 1 - p 19-23
Review Article
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Light to moderate alcohol consumption is associated with a reduced risk of coronary heart disease, as well as ischaemic stroke and possibly type 2 diabetes. Epidemiological and physiological data are in favour of a causal relationship. Proposed protective mechanisms include the stimulation of HDL-mediated processes such as reverse cholesterol transport and antioxidative effects. More well-controlled studies are needed to provide a complete understanding of the complexity of the underlying physiological mechanisms.

aDepartment of Biochemistry, Cardiovascular Research Institute, Erasmus University Rotterdam, the Netherlands, bTNO Nutrition and Food Research, Department of Nutritional Physiology, Zeist, the Netherlands

Correspondence to Arie van Tol, Department of Biochemistry, Cardiovascular Research Institute, Erasmus University Rotterdam, PO Box 1738, 3000 DR Rotterdam, the Netherlands. Tel: +31 10 408 7321; fax: +31 10 408 9472; e-mail: VANTOL@BC1.FGG.EUR.NL

© 2001 Lippincott Williams & Wilkins, Inc.